Methacholine and macrolides
نویسندگان
چکیده
منابع مشابه
Methacholine and Macrolides
study are relevant, I believe that the design of the study was not adequate to answer these questions. First, all patients were on NM for w3 months and one patient even for 70 months, whereas they trained only for 1 day on FFM. In our centre (Dept of Pulmonary Diseases/ Home mechanical ventilation, University Hospital Groningen, Groningen, The Netherlands), patients routinely need more time (y7...
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Three pharmacokinetic/pharmacodynamic parameters--(i) the peak concentration to the minimum inhibitory concentration ratio (C(max)/MIC); (ii) the area under the concentration-time curve to MIC ratio (AUC(24h)/MIC); and (iii) the time the concentration exceeds the MIC (T>MIC)--are important predictors of the clinical efficacy of antibiotics. For antibiotics with pronounced concentration-dependen...
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Community acquired pneumonia (CAP) is increasing in incidence, and is presently responsible for about 1% of emergency medical admissions with an associated mortality of between 5% and 24%. Improving the outcome of CAP is, therefore, a major health priority, but what is the best method to do this? Many audits have shown poor adherence to national guidelines for the management of CAP, with the in...
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Erythromycin was the first macolide discovered in 1952. In 1990s new macrolides including clarithromycin, azithromycin, and dirithromycin were introduced to the market. We provide a review of their structure, pharmacokinetics, mechanisms of action, and indications in dermatology.
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REFERENCES 1 Leyten EMS, Prins C, Bossink AWJ, et al. Effect of tuberculin skin testing on a Mycobacterium tuberculosis-specific interferon-c assay. Eur Respir J 2007; 29: 1212–1216. 2 National Institute for Health and Clinical Excellence. Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control. Clinical Guideline 33. National Institute for C...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2004
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.04.10057104